Download 20 Things to Know about Deep Brain Stimulation by Erwin B. Montgomery Jr. PDF

By Erwin B. Montgomery Jr.

Twenty issues to understand approximately Deep mind Stimulation is an in depth and in-depth serious research of the sector of Deep mind Stimulation (DBS) from what many may perhaps give some thought to a innovative point of view. This ebook demonstrates the original nature and superb promise of DBS and indicates the way it is exceptional as a healing intervention. Dr. Montgomery presents an epistemic research of the presuppositions, assumptions and fallacies underlying present scientific figuring out of DBS in addition to the body structure and pathophysiology tormented by DBS. stories of the protection and efficacy for a couple of stipulations, sufferer choices and concerns within the post-operative administration also are integrated. Given the innovative strength and the complexity of DBS in an ever altering healthcare supply context, the ethics of DBS are mentioned intimately.

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Extra resources for 20 Things to Know about Deep Brain Stimulation

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2007; Dams et al. 2013). Further, DBS provides better symptom relief than pharmacological treatments for many disorders. DBS provides an opportunity to reexamine many of the assumptions and presumptions affecting the presumptions and assumptions operative in acceptance of therapies by physicians and healthcare professionals. As is discussed later in this chapter, notions of pathophysiology plays a significant role in acceptance of new therapies. These issues play out most clearly in Parkinson’s disease, but the same issues are relevant for brain disorders in general.

For example, hypertension may confound studies of stroke prevention. Consequently, the hope is that randomization will result in as many patients with hypertension in the experimental group as are in the control group. However, an individual patient simultaneously has and does not have hypertension. The RCT provides no means by which to determine the effect of the confound so that it may aid the care of the individual patient (see discussion in c­ hapter 15 regarding population statistics and the Second Law of Thermodynamics).

This success thus argues for the existence of some novel mechanism of disease affected by DBS that, in the case of Parkinson’s disease, is not inherently neurochemical. Some 160 years after Luigi Galvani established the importance of electricity and electronics in animal behaviors by eliciting them with external electrical stimulation, the discovery of chemical neurotransmission served to diminish this importance. Interestingly, initial evidence of chemical neurotransmission arose from an equating of the effects of the chemical acetylcholine on the heart to the effects of electrically stimulating the vagus nerve (Valenstein 2005).

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