By Hiroshi Mitsumoto MD
Amyotrophic Lateral Sclerosis offers the main complete, clinically-focused details on ALS (Lou Gehrig's disorder) in print. the 3 authors, widely recognized for his or her paintings during this sector, offer cohesive and balanced assurance of this syndrome, together with the background, scientific positive factors, pathology and pathogenesis, therapy and administration of ALS. To facilitate figuring out, each one bankruptcy is improved via finished tables and figures, in addition to certain bankruptcy summaries.
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Additional resources for Amyotrophic Lateral Sclerosis
In this book, we use the following definitions: Motor neuron diseases (MNDs) are a heterogeneous group of disorders with diverse signs and symptoms, all in some way affecting the anterior horn cells. Amyotrophic lateral sclerosis (ALS) is the most common form of MND of undetermined cause in adults, affecting not only the anterior horn cells but also the corticospinal tracts, resulting in a fairly consistent clinical picture and outcome. Whether ALS is a single disease entity or a syndrome caused by a number of different conditions remains to be determined.
Fromann, M: Atrophie musculaire progressive (autopsie). Med Chir Mschr 1 (1858) summary in Arch Gen Med 13:96, 1859. 25. Gajdusek, DC: Motor-neuron disease in native of New Guinea. N Engl J Med 268:474-476, 1963. 26. Gajdusek, DC and Salazar, AM: Amyotrophic lateral sclerosis and parkinsonian syndromes in high incidence among the Auyu and Jakai people of West New Guinea. Neurology 32:107-126, 1982. 27. Goldblatt, D: Motor neuron disease: Historical introduction. In Norris, FH and Kurland, LT (eds): Motor Neuron Diseases.
Jean Martin Charcot60 A BRIEF HISTORY OF ALS Before Charcot Charcot's Contribution Nosologic Controversy Primary Lateral Sclerosis Motor System Degeneration, Motor Neuron Disease, or ALS? New Forms of ALS TERMINOLOGY AND DEFINITIONS Motor Neuron Disease and ALS Description of ALS Subsets WORLD FEDERATION OF NEUROLOGY CLASSIFICATION This chapter briefly reviews the history of amyotrophic lateral sclerosis (ALS). The initial history of ALS is characterized by a series of events that established the nosology.